MSMS 6211, BCOR 5585 Genomics
Other Course Guides
Genomics
Genomics
MSMS 6211, BCOR 5585
Fall 2023
The primary goal of this course is to introduce and describe the latest advances in molecular biology, genomics, computational biotechnology, and their interrelationships to all biology and human society through classroom and computer exercises. We will review milestone discoveries, which led to the rise of genomics science, characteristics of the wide spectrum of different genomes (prokaryotic, eukaryotic and organellar), and innovative molecular techniques and tools (e.g. high throughput DNA sequencing, CRISPRs) used to study and manipulate genomes. We will study genomes including their architecture in different organisms and the gene products that underlie development and basic metabolism. Genomics will also be viewed in the context of “Big Data” sets, and its integration with computational methods. The impact of genomics on human health (personalized medicine, diagnostics and new treatments to cure genetic diseases), ecology, ethical issues and problems will be discussed in depth.
Required Textbook:
The Genome Generation by
The year 2001 marked the moment when scientists first read the 3 billion letters of DNA that make up the human genome. This breakthrough begged questions such as What have we learned about evolution? How has it changed the way we practice medicine, grow crops, and breed livestock? and Is the genomic revolution an overhyped flop? Answering these and many other queries, this account covers revolutionary genetic developments in areas as diverse as medicine, agriculture, and evolution. From Botswana to Boston and from Australia to Mexico, the contributors to this work reveal what it means to be part of the genome generation.
Call Number: QH447 .F56 2012ISBN: 9780522856477Publication Date: 2012-04-01- The Genome Generation by
The year 2001 marked the moment when scientists first read the 3 billion letters of DNA that make up the human genome. This breakthrough begged questions such as What have we learned about evolution? How has it changed the way we practice medicine, grow crops, and breed livestock? and Is the genomic revolution an overhyped flop? Answering these and many other queries, this account covers revolutionary genetic developments in areas as diverse as medicine, agriculture, and evolution. From Botswana to Boston and from Australia to Mexico, the contributors to this work reveal what it means to be part of the genome generation.
Call Number: AVAILABLE FOR PURCHASE ONLINEISBN: 9780522856477Publication Date: 2012-04-01
Recommended Textbooks:
Who We Are and How We Got Here: Ancient DNA and the New Science of the Human Past by Call Number: E-BOOKISBN: 9781101870334Publication Date: 2018
Bioinformatics and Functional Genomics by
The bestselling introduction to bioinformatics and genomics - now in its third edition Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research. This book provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include: Extensive revisions and a slight reorder of chapters for a more effective organization A brand new chapter on next-generation sequencing An expanded companion website, also updated as and when new information becomes available Greater emphasis on a computational approach, with clear guidance of how software tools work and introductions to the use of command-line tools such as software for next-generation sequence analysis, the R programming language, and NCBI search utilities The book is complemented by lavish illustrations and more than 500 figures and tables - many newly-created for the third edition to enhance clarity and understanding. Each chapter includes learning objectives, a problem set, pitfalls section, boxes explaining key techniques and mathematics/statistics principles, a summary, recommended reading, and a list of freely available software. Readers may visit a related Web page for supplemental information such as PowerPoints and audiovisual files of lectures, and videocasts of how to perform many basic operations: www.wiley.com/go/pevsnerbioinformatics. Bioinformatics and Functional Genomics, Third Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.
Call Number: E-BOOKISBN: 9781118581766Publication Date: 2015-08-17- Bioinformatics and Functional Genomics by
The bestselling introduction to bioinformatics and genomics - now in its third edition Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research. This book provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include: Extensive revisions and a slight reorder of chapters for a more effective organization A brand new chapter on next-generation sequencing An expanded companion website, also updated as and when new information becomes available Greater emphasis on a computational approach, with clear guidance of how software tools work and introductions to the use of command-line tools such as software for next-generation sequence analysis, the R programming language, and NCBI search utilities The book is complemented by lavish illustrations and more than 500 figures and tables - many newly-created for the third edition to enhance clarity and understanding. Each chapter includes learning objectives, a problem set, pitfalls section, boxes explaining key techniques and mathematics/statistics principles, a summary, recommended reading, and a list of freely available software. Readers may visit a related Web page for supplemental information such as PowerPoints and audiovisual files of lectures, and videocasts of how to perform many basic operations: www.wiley.com/go/pevsnerbioinformatics. Bioinformatics and Functional Genomics, Third Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.
Call Number: QH441.2 .P48 2015ISBN: 9781118581766Publication Date: 2015-08-17
At the conclusion of this course the student will be able to:
- Demonstrate proficient library and computer skills in data gathering and analysis.
- Analyze macromolecular sequences in the context of specific biological questions.
- Navigate and apply diverse, modern genetic databases and software to specific questions.
- Apply current bioinformatics and genomics methods to current organismal systems and problems.
- Prepare oral and written reports in an acceptable standard scientific format.
- Understand some of the larger questions and issues within genomics and large scale data collection and analysis.
- Learn to work and cooperate as part of an interdisciplinary team.
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